New PDF release: Comparative Physiology of the Vertebrate Kidney

By William H. Dantzler

ISBN-10: 364283521X

ISBN-13: 9783642835216

ISBN-10: 3642835236

ISBN-13: 9783642835230

This quantity emphasizes the comparative method of lower thanĀ­ status vertebrate renal functionality. i'm confident that this procedure is of specific worth in figuring out either the main points of renal functionality on the mobile and subcellular degrees and the renal position in regulating fluid volumes and solute concentrations. My publicity to this process first happened in the course of a pupil examine adventure within the laboratory of Wilbur H. Sawyer, who additionally supplied an advent to the works of Homer W. Smith and August Krogh. the significance of this method was once bolstered by way of doctoral and postdoctoral learn within the laboratory of Bodil Schmidt-Nielsen. it's been proven via years of private adventure on the grounds that then. My learn and my knowing of renal functionality were aided over the years through collaboration and dialogue with various scholars and co-workers. Of specific imporĀ­ tance in constructing my perspectives on comparative renal functionality, and particularly at the dating of constitution to operate, has been my lengthy organization with my colleague and good friend, Eldon J. Braun. Donald S. Farner, who urged the writing of this quantity, supplied helpful editorial suggestions. a lot of my own study during this quarter has been supported through the years via delivers from the U.S. nationwide technology origin and nationwide Institutes of healthiness. The writing of this quantity was once accomplished whereas i used to be in Wiirzburg, Federal Republic of Germany, supported through a Senior U.S. Scientist Award from the Alexander von Humboldt Foundation.

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Extra resources for Comparative Physiology of the Vertebrate Kidney

Example text

Unfortunately, as noted above, there are no really accurate measurements of the area available for filtration for any species. In the one species of fish, the primitive, anadromous river lamprey (L. f/uviatilis), in which filtration has been evaluated by micropuncture, the attainment of filtration equilibrium depends on whether the animals are adapted to freshwater or brackish water (McVicar and Rankin 1985). In freshwater-adapted animals, filtration equilibrium is not achieved along the glomerular capillaries, i.

S. cyanogenys) also contain light and dark cells that may correspond to the principal cells and intercalated cells described in other species (Davis et al. 1976). However, the light cells appear to be mucus-secreting (Davis et al. 1976). Dark or intercalated cells also begin to appear at the end of the distal tubule of birds, apparently marking the transition into the collecting tubule or duct (Nicholson 1982). However, the avian collecting tubule or duct contains mucin-secreting cells as well as these dark cells; the mucin-secreting cells become the prominent type in the more distal portions of the collecting-duct system (Nicholson 1982).

However, the cells of the late distal tubule of amphibians are much taller than those of the early distal tubule and have very large nuclei and very deep basal infoldings (Fig. 15; also Stanton et al. 1984a). The cells of the late distal tubule of some fishes (e. g. , Polypterus sengalus) and of some saurian reptiles (e. , S. cyanogenys) are also taller than those of the early distal tubule and have less marked lateral interdigitations (Davis et al. 1976; Hentschel and Elger 1987). 16. Schematic of juxtaglomerular apparatus.

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Comparative Physiology of the Vertebrate Kidney by William H. Dantzler


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