Bioinformatics: A Practical Guide to the Analysis of Genes by Andreas D. Baxevanis, B. F. Francis Ouellette PDF

By Andreas D. Baxevanis, B. F. Francis Ouellette

ISBN-10: 0471383910

ISBN-13: 9780471383918

"In this publication, Andy Baxevanis and Francis Ouellette . . . have undertaken the tough activity of organizing the information during this box in a logical development and proposing it in a digestible shape. and so they have performed a great task. This effective textual content will make an immense influence on organic learn and, in flip, on growth in biomedicine. we're all of their debt."
—Eric Lander from the Foreword
Reviews from the 1st Edition
"...provides a huge evaluate of the elemental instruments for series research ... For biologists coming near near this topic for the 1st time, it will likely be a truly helpful instruction manual to maintain at the shelf after the 1st examining, on the subject of the computer."
Nature Structural Biology
"...should be within the own library of any biologist who makes use of the net for the research of DNA and protein series data."
Science
"...a fabulous primer designed to navigate the beginner in the course of the intricacies of in scripto research ... The finished gene searcher also will locate this e-book an invaluable addition to their library ... an exceptional connection with the foundations of bioinformatics."
Trends in Biochemical Sciences
This new version of the hugely profitable Bioinformatics: a realistic advisor to the research of Genes and Proteins presents a legitimate starting place of simple thoughts, with useful discussions and comparisons of either computational instruments and databases correct to organic research.
Equipping biologists with the trendy instruments essential to remedy functional difficulties in series information research, the second one version covers the large spectrum of themes in bioinformatics, starting from web strategies to predictive algorithms used on series, constitution, and expression information. With chapters written by means of specialists within the box, this updated reference completely covers very important thoughts and is suitable for either the beginner and the skilled practitioner. Written in transparent, uncomplicated language, the booklet is available to clients with no a sophisticated mathematical or desktop technological know-how history. This re-creation includes:* All new end-of-chapter net assets, bibliographies, and challenge units* Accompanying site containing the solutions to the issues, in addition to hyperlinks to proper internet assets* New insurance of comparative genomics, large-scale genome research, series meeting, and expressed series tags* A word list of known phrases in bioinformatics and genomics
Bioinformatics: a realistic advisor to the research of Genes and Proteins, moment version is vital interpreting for researchers, teachers, and scholars of all degrees in molecular biology and bioinformatics, in addition to for investigators enthusiastic about genomics, positional cloning, scientific learn, and computational biology.

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Additional info for Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins (2nd Edition)

Sample text

The length is obviously known in this case, matching the number of bases or residues in the sequence. Segmented Bioseq. A segmented Bioseq does not contain raw sequences but instead contains the identifiers of other Bioseqs from which it is made. This type of Bioseq can be used to represent a genomic sequence in which only the exons are known. The ‘‘parts’’ in the segmented Bioseq would be the individual, raw Bioseqs representing the exons and the virtual Bioseqs representing the introns. Delta Bioseq.

PMID serves the same purpose as MUID in providing a simple, reliable link to the citation, a means of linking records together, and a means of setting up hyperlinks. Publishers have also started to send information on ahead-of-print articles to PubMed, so this information may now appear before the printed journal. A new project, PubMed Central, is meant to allow electronic publication to occur in lieu of or ahead of publication in a traditional, printed journal. PubMed Central records contain the full text of the article, not just the abstract, and include all figures and references.

The delta sequence is used for unfinished high-throughput genome sequences (HTGS) from genome centers and for genomic contigs. Team-Fly® BIOSEQs: SEQUENCES 33 34 T H E N C B I D ATA M O D E L Raw Bioseq. This is what most people would think of as a sequence, a single contiguous string of bases or residues, in which the actual sequence is known. The length is obviously known in this case, matching the number of bases or residues in the sequence. Segmented Bioseq. A segmented Bioseq does not contain raw sequences but instead contains the identifiers of other Bioseqs from which it is made.

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Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins (2nd Edition) by Andreas D. Baxevanis, B. F. Francis Ouellette


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