By Sophie Delaplaine
A professional bartender who earned her stripes operating within the scorching golf equipment and bars of Miami's South seashore finds the secrets and techniques to luck within the bar and eating place enterprise.
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Extra info for Bartending Your Way To Millions
Common names are shown in parentheses if they are available in the Taxonomy database. The lineage above Hominidae is shown in the line at the top of the display; selecting the word Lineage will toggle back and forth between the abbreviated lineage (the display used in GenBank flatfiles) and the full lineage (as it appears in the Taxonomy database). Selecting any of the taxa above Hominidae (in the lineage) or below Hominidae (in the hierarchical display) will refocus the browser on that taxon instead of the Hominidae.
Note that CD links can be identified even when no 3D structures within a family are known. Moreover, 3D Domain links may also indicate relationships either to structures not included in CDD entries or to structures so distantly related that no significant similarity can be found by sequence comparisons. Finding and Viewing Structures For an example query on finding and viewing structures, see Box 2. Why Would I Want to Do This? • To determine the overall shape and size of a protein • To locate a residue of interest in the overall structure • To locate residues in close proximity to a residue of interest • To develop or test chemical hypotheses regarding an enzyme mechanism • To locate or predict possible binding sites of a ligand • To interpret mutation studies • To find areas of positive or negative charge on the protein surface • To locate particularly hydrophobic or hydrophilic regions of a protein • To infer the 3D structure and related properties of a protein with unknown structure from the structure of a homologous protein • To study evolutionary processes at the level of molecular structure • To study the function of a protein • To study the molecular basis of disease and design novel treatments How to Begin The first step to any structural analysis at NCBI is to find the structure records for the protein of interest or for proteins similar to it.
Find the Taxonomy update frequency by selecting Entrez Date from the pull-down menu under Preview/Index, typing “2002/02” in the box and selecting Index. com The NCBI Handbook The Taxonomy Project 2002/01 (5176) 2002/01/03 (478) 2002/01/08 (2) 2002/01/10 (2260) 2002/01/14 (7) 2002/01/16 (239) shows that in January 2002, 5,176 new taxa were added, the bulk of which appeared in Entrez for the first time on January 10, 2002. These taxa can be retrieved by selecting 2002/01/10, then selecting the AND button above the window, followed by Go.
Bartending Your Way To Millions by Sophie Delaplaine